CJC-1295 No DAC 5mg + Ipamorelin 5mg (10mg Blend) Dosage Protocol

Quickstart Highlights

This research blend combines CJC-1295 (No DAC), a modified growth hormone-releasing hormone (GHRH) analog, with Ipamorelin, a selective growth hormone secretagogue (GHS). Together, these compounds are commonly studied for their ability to support natural growth hormone signaling pathways.

CJC-1295 (No DAC) is known for producing sustained, dose-dependent increases in growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels. Ipamorelin works synergistically by stimulating GH release in a highly selective manner, without significantly impacting ACTH or cortisol levels.

When used together, these compounds support increased GH and IGF-1 levels through complementary pathways, resulting in a more sustained and efficient hormonal response.

This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.


Reconstitution & Basic Usage
  • Reconstitute: Add 2.0 ml bacteriostatic water →   ~5 mg/mL total concentration (2.5 mg/mL each peptide).
  • Typical daily range: 500 mcg (250 mcg of each peptide) once daily (gradual titration).
  • Easy measuring: At 5 mg/ml total, 1 unit = 0.01 ml ≈ (50 mcg) 25 mcg of each peptide on a U-100 insulin syringe.
  • Storage
    • Lyophilized: store at or below −15°C (5°F)
    • Reconstituted: store at 2–8°C (35.6–46.4°F)

Dosing & Reconstitution Guide

Educational guide for reconstitution and daily dosing

10mg Blend Vial (5mg CJC-1295 + 5mg Ipamorelin)
2ml BAC water = 5mg/ml concentration

Protocol Dose (mcg) / Units Frequency
Starting* 500 mcg (10 Units) 5x/week
Intermediate 750 mcg (15 Units) 5x/week
Advanced 1 mg (20 Units) 5x/week

Frequency:
Administered 5x per week via subcutaneous injection, most commonly in the evening to align with the body’s natural nighttime growth hormone rhythm.

Dosing Approach:
Many individuals remain at their initial dose for extended periods without increasing, focusing on consistency and tolerance rather than escalation.

Fasted State Recommended:
For best results, avoid food intake for approximately 2–3 hours prior to administration.

Common Sensations:
A temporary warm or flushed feeling in the face may occur shortly after use. This is a commonly reported, short-lived response.

Hydration Matters:
Maintaining adequate water intake is important, as some individuals may experience mild dehydration if fluid intake is insufficient.

Reconstitution Steps

  • Draw 2.0 mL of bacteriostatic water using a sterile syringe
  • Slowly inject the water into the vial along the inner wall
  • Gently swirl or roll the vial until fully dissolved (do not shake)
  • Store in the refrigerator (2–8°C), away from light

Important: This guide is for educational purposes only and is not medical advice. For research use only. Not for human consumption.

Supplies Needed

Plan is based on an 8–16 week 5x per week protocol taking the standard dose

10mg Blend Vial (5mg CJC-1295 + 5mg Ipamorelin)

  • 8 weeks → 2 vials
  • 12 weeks → 3 vials
  • 16 weeks → 4 vials

Insulin Syringes

  • 8/week total
  • 8 weeks → 40
  • 12 weeks → 60
  • 16 weeks → 80

Bacteriostatic Water

  • 8 weeks: ~6 mL (1 bottle)
  • 12 weeks: ~9 mL (1 bottle)
  • 16 weeks: ~12 mL (2 bottles)

Alcohol Swabs

  • 8 weeks → ~40
  • 12 weeks → ~60
  • 16 weeks → ~80

Protocol Overview

  • Goal: Support natural growth hormone release and improve recovery, body composition, and metabolic health
  • Schedule: Daily injections for 8–12 weeks (extendable to 16 weeks)
  • Dose Range: 500 mcg (250 mcg of each peptide) 5x per week
  • Reconstitution: 2.0 mL per vial
  • Storage: Refrigerated after mixing; avoid repeated freeze–thaw

Dosing Protocol

Example of a weekly strategy:

  • Start: 500 mcg (10 Units) 

  • Frequency: Monday – Friday at 11pm, 3 hours after last meal

  • Cycle Length: 8–12 weeks (optional 16-week extension)

Storage Instructions

Maintaining proper storage conditions is essential for stability.

  • Lyophilized: Store at ≤−20 °C, dry and protected from light

  • Reconstituted: Refrigerate (2–8 °C), use within ~2–4 weeks

  • Avoid repeated freeze–thaw cycles

  • Allow vial to reach room temperature before opening

Important Notes

Key considerations for consistency and safe handling:

  • Use a new sterile syringe for each use

  • Rotate injection sites to minimize irritation

  • Inject slowly and steadily

  • Track dosage and timing for consistency

  • Use smaller syringes for low-volume accuracy

How This Works

CJC-1295 No DAC is a modified GHRH analog that stimulates pulsatile growth hormone release by binding to pituitary receptors. Its short-acting nature allows for controlled GH secretion patterns without prolonged exposure.

Ipamorelin is a selective ghrelin receptor (GHS-R1a) agonist that triggers GH release through a separate pathway, without significantly affecting cortisol or other hormones in research models.

When combined, these peptides enable the study of:

  • Dual receptor activation (GHRH + GHS)

  • Enhanced GH pulsatility

  • IGF‑1 and IGFBP-3 response patterns

  • Endocrine feedback regulation

Potential Benefits & Side Effects

Observed Effects in Literature:

  • Increased GH and IGF‑1 signaling

  • Improved hormone pulsatility patterns

  • Selective GH release via Ipamorelin pathway

  • Synergistic receptor interaction

Reported Reactions (generally mild):

  • Injection site irritation

  • Temporary flushing or headache

  • Occasional appetite changes or fluid retention

Lifestyle Factors

Supporting variables that may improve research consistency:

  • Maintain structured nutrition protocols for consistency

  • Include resistance and aerobic activity in study design

  • Prioritize sleep (linked to GH release cycles)

  • Control stress variables for hormonal stability

Injection Technique

General guidance for subcutaneous administration:

  • Clean the vial stopper and injection area with alcohol and allow to dry
  • Gently pinch the skin and insert the needle at a 45–90° angle
  •  Inject slowly and steadily without aspirating
  • Hold the needle in place for a few seconds before removing
  • Rotate injection sites (abdomen, thighs, upper arms) to reduce irritation

We recommend Fit Aminos for high-purity research peptide products CJC-1295 No DAC 5mg+ Ipamorelin 5mg – (10mg Blend)

Why Fit Aminos?

  • High-purity, lab-tested peptide batches with quality verification.
  • Consistent handling and preparation processes designed to support reliable research protocols.
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Important Note

This content is intended for educational and research purposes only and does not constitute medical advice, diagnosis, or treatment. CJC-1295 No DAC 5mg+ Ipamorelin 5mg – (10mg Blend)  remains an investigational peptide with limited human clinical data. For research use only. Not for human consumption.

References

PubMed— Clinical study demonstrating that CJC-1295 significantly increases and sustains growth hormone (GH) and IGF-1 levels in healthy adults.

PubMed— Preclinical research showing that once-daily CJC-1295 restores normal growth patterns in GHRH-deficient animal models

PubMed— Foundational study identifying Ipamorelin as a highly selective growth hormone secretagogue with targeted receptor activity and minimal off-target effects.

PMC (PubMed Central)
— Review exploring the role of growth hormone secretagogues in improving body composition, metabolic function, and endocrine system regulation.

PubMed— Study analyzing the pharmacokinetics and pharmacodynamics of Ipamorelin, including its absorption, distribution, and GH response profile in human subjects.

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